Spermidine-Rich Foods Have Many Anti-Aging And Longevity Benefits

Published: October 12, 2023

Spermidine-rich foods have recently gained attention for their potential anti-aging and longevity benefits. This naturally occurring compound can be found in various foods, including aged cheese, mushrooms, soy products, legumes, corn, and whole grains. Consuming foods high in spermidine may help support overall health and wellness.

Increasing your intake of spermidine-rich foods can positively impact your body due to the compound’s ability to promote cellular health and combat aging processes. By incorporating more of these foods into your daily diet, you can experience reduced inflammation, protection against liver disease, and an extended lifespan.

While more research is needed to fully understand the benefits and optimal levels of spermidine consumption, it is clear that embracing a diet rich in spermidine containing foods is a promising approach to supporting your body’s natural functions and promoting a healthier lifestyle.

Top 16 Foods Highest in Spermidine

In this section, you will find a list of 16 foods high in spermidine content, which can provide various health benefits. In concise tables, we will briefly introduce other ingredients in these foods and their main benefits.  Be sure to buy none GMO, or organic.

Wheat Germ

Wheat germ is a spermidine-rich food containing approximately 246 mg/kg of spermidine.

Ingredient Benefit
Fiber Supports digestion and heart health
Protein Helps build and maintain muscle tissue
Vitamin E Functions as an antioxidant, protecting cells

Soybeans

None-GMO Soybeans provide about 207 mg/kg of spermidine.

Ingredient Benefit
Protein Essential for muscle and tissue growth
Fiber Aids digestion and supports heart health
Isoflavones Associated with reduced heart disease risk

Cheddar

Cheddar cheese contains around 2.7 mg/100g of spermidine.

Ingredient Benefit
Calcium Promotes strong bones and teeth
Protein Contributes to muscle and tissue growth
Vitamin B12 Supports brain function and energy metabolism

Mushrooms

Mushrooms, like Black Shimeji, deliver more than 120 mg/kg of spermidine.

Ingredient Benefit
Vitamin B3 Improves cholesterol levels and brain function
Vitamin D Helps maintain bone health and immune function
Selenium Acts as an antioxidant and supports thyroid function

Rice Bran

Rice bran offers a spermidine content of about 189 mg/kg.

Ingredient Benefit
Fiber Promotes healthy digestion and heart health
Vitamin B6 Supports brain health and energy production
Magnesium Helps maintain muscle and nerve function

Chicken Liver

Chicken liver contains approximately 69 mg/kg of spermidine.

Ingredient Benefit
Vitamin A Supports vision, immune function, and cell growth
Vitamin B12 Boosts brain function and energy metabolism
Iron Enhances oxygen transport and supports energy production

Green Peas

Green peas contribute more than 50 mg/kg of spermidine.

Ingredient Benefit
Fiber Aids digestion and promotes heart health
Protein Supports muscle and tissue growth
Vitamin K Essential for blood clotting and bone health

Mango

Mangoes provide a spermidine content of around 398 nmol/g.

Ingredient Benefit
Vitamin C Supports immune function and collagen production
Vitamin A Aids vision, immune function, and cell growth
Folate Promotes healthy red blood cell production

Chickpea

Chickpeas contain spermidine levels reaching up to 50 mg/kg.

Ingredient Benefit
Protein Encourages muscle and tissue growth
Fiber Promotes digestion and heart health
Iron Essential for oxygen transport and energy production

Cauliflower (Cooked)

Cooked cauliflower offers a spermidine content of approximately 398 nmol/g.

Ingredient Benefit
Vitamin C Assists immune function and collagen production
Vitamin K Crucial for blood clotting and bone health
Choline Supports brain function and cell membrane maintenance

Corn

None-GMO Corn contains up to 50 mg/kg of spermidine.

Ingredient Benefit
Fiber Aids digestion and heart health
Vitamin B3 Helps improve brain function and cholesterol levels
Carotenoids Function as antioxidants protecting cells

Lentils

Lentils provide spermidine levels of around 50 mg/kg.

Ingredient Benefit
Protein Contributes to muscle and tissue growth
Fiber Promotes healthy digestion and heart health
Iron Enhances oxygen transport and supports energy production

Cheese

Cheeses like aged varieties can offer 2.7 mg/100g of spermidine.

Ingredient Benefit
Calcium Strengthens bones and teeth
Protein Supports muscle and tissue growth
Vitamin B12 Boosts brain function and energy metabolism

Broccoli (Cooked)

Cooked broccoli has a spermidine content of about 398 nmol/g.

Ingredient Benefit
Vitamin C Assists immune function and collagen production
Vitamin K Essential for blood clotting and bone health
Folate Promotes healthy red blood cell production

Green Tea

Green tea contains trace amounts of spermidine.

Ingredient Benefit
Antioxidants Protects cells from damage and aging
L-theanine Enhances relaxation and focus without drowsiness
Catechins May promote fat oxidation and weight loss

Natto

Natto is high in spermidine, reaching up to 115 mg/kg.

Ingredient Benefit
Vitamin K2 Supports bone health and prevents calcification
Protein Encourages muscle and tissue growth
Probiotics Aid digestion and support immune function

Other Foods with Moderate Levels of Spermidine

While certain foods like aged cheese, mushrooms, soy products, and whole grains are known for their higher spermidine content, others contain moderate levels of this beneficial polyamine. Incorporating various sources in your diet can help you get the required spermidine intake for its potential health benefits.

Lentils contain around 39.1 mg/kg of spermidine1. In addition to spermidine, lentils are rich in protein, fiber, and essential vitamins and minerals such as iron, potassium, and folate.

Hazelnuts have a spermidine content of approximately 8.9 mg/kg1. Apart from spermidine, hazelnuts are an excellent source of healthy fats, vitamins E, and B, and minerals like magnesium and copper.

Grapefruits provide around 4.6 mg/kg of spermidine. They offer moderate spermidine and are packed with vitamin C, fiber, and antioxidants.

Here’s a brief table summarizing the additional benefits of these foods:

Food Main Benefits
Lentils Protein, fiber, iron, potassium, folate
Hazelnuts Healthy fats, vitamins E and B, magnesium, copper
Grapefruits Vitamin C, fiber, antioxidants

Maintaining a balanced diet with various food sources is essential to enjoy the full range of nutrients, including spermidine. Including these moderately spermidine-rich foods can help you achieve the necessary intake for potential health benefits.

Spermidine Recipes and Meal Ideas

Spermidine-Rich Breakfast Recipes

Start your day with a healthy breakfast with spermidine-rich foods to support longevity. You can try the following meal ideas:

  • A bowl of whole-grain cereal or oatmeal topped with wheat germ, chopped nuts, and seeds like sunflower or pumpkin seeds. Add some fresh mango for extra spermidine content and natural sweetness.
  • A savory breakfast stir-fry featuring mushrooms, broccoli, onions, and soybeans sauteed in a bit of oil. Serve this protein-packed dish with whole-grain toast or a side of brown rice.

Spermidine-Rich Lunch and Dinner Recipes

Incorporate spermidine-rich foods into your lunch and dinner meals with these ideas:

  • A hearty spermidine-rich stew consisting of carrots, potatoes, broccoli, mushrooms, onion, and celery. Cook it in oil and butter, and thicken with a roux. Check out this spermidine-rich stew recipe for detailed instructions.
  • A mixed salad featuring fresh or steamed vegetables like broccoli or other cruciferous vegetables, sliced mushrooms, and grated aged cheese. Top this off with a handful of hazelnuts for a tasty crunch and additional spermidine content.

Spermidine-Rich Snack Ideas

If you’re looking for quick and easy spermidine-rich snacks, try the following options:

  • Nuts and seeds: Enjoy a handful of hazelnuts or a mix of sunflower and pumpkin seeds to boost spermidine.
  • Aged cheese: Moderate a small serving of aged cheese, as it can also be high in calories and saturated fats.
  • None-GMO Soy products: Snack on edamame, soy nuts, or a small serving of tofu for a healthy and spermidine-rich option.

Spermidine-Rich Beverage Options

Not many beverages are naturally rich in spermidine, but you can still choose options that support your overall health and pair well with other spermidine-rich foods. Some ideas include:

  • Green tea: Known for its antioxidants and potential health benefits, it can greatly accompany your spermidine-rich meals.
  • Smoothies: Whip up a smoothie using fruits and vegetables with higher spermidine content, like mangoes or leafy greens. You can also add ingredients like wheat germ or soy milk to increase the spermidine content further.

By incorporating these meal ideas and snacks into your diet, you’re taking steps towards embracing the potential benefits of spermidine and supporting your overall health and well-being.

Spermidine Supplements: Are They Necessary?

Spermidine is a naturally occurring compound that serves several vital roles in the functioning of cells. It can be found in many foods, including vegetables and whole grains; however, must be noted that all supplements / vitamins are synthesized and processed, to make them look like original, but would never behave as the real naturally occurring substance. Also synthesized supplements are hazardous to your health.

Dietary Sources of Spermidine

Since both plant and animal-based foods are excellent sources of spermidine and related polyamine compounds, these dietary options should be considered before taking supplements. Some of the most spermidine-rich foods are:

  • Soybeans
  • Mushrooms
  • Whole grains
  • Legumes
  • Leafy greens
  • Aged cheeses

Popular Spermidine Content in Supplements

Popular spermidine supplements come in varying percentages, with 99% and 1% being some common examples. These supplements may contain natural spermidine powder derived from plant sources or synthetic spermidine created in a laboratory.

The forms of spermidine in supplements can vary. For example, some supplements may contain spermidine extract, while others may use powdered spermidine-rich ingredients.

Popular Ingredients Formulated with Spermidine in Supplements

In addition to pure spermidine content, some supplements may also include additional ingredients to enhance their effectiveness, such as:

  • Antioxidants
  • Vitamins and minerals
  • Digestive enzymes
  • Probiotics

These ingredients work with spermidine to support cell health and promote overall well-being. Research and consult a healthcare professional before starting a supplementation routine to ensure it suits your needs. Remember that a balanced diet rich in spermidine-containing foods should always be the foundation for optimal health.